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1

In Vitro, In Vivo and In Silico Analysis of the Anticancer and Estrogen-like Activity of Guava Leaf Extracts

Rizzo, L.Y., Longato, G.B., Ruiz, A.LT.G., Tinti, S.V., Possenti, A., Vendramini-Costa, D.B., Sartoratto, A., Figueira, G.M., Silva, F.L.N., Eberlin, M.N., Souza, T.A.C.B., Murakami, M.T., Rizzo, E.,

Journal:

Current Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 3.23 MB

english, 2014

2

Molecular Link Mechanisms between Inflammation and Cancer

B. Vendramini-Costa, D., E. Carvalho, J.

Journal:

Current Pharmaceutical Design

Year:

2012

Language:

english

File:

PDF, 497 KB

english, 2012

3

Synthesis of thiophene-thiosemicarbazone derivatives and evaluation of their in vitro and in vivo antitumor activities

J. F. De Oliveira, A. L. Da Silva, D. B. Vendramini-costa, C. A. Da Cruz Amorim, J. F. Campos, A. G. Ribeiro, R. Olímpio De Moura, J. L. Neves, A. L. Tasca Gois Ruiz, J. Ernesto De Carvalho, M. Do Car

Year:

2015

Language:

english

File:

PDF, 3.50 MB

english, 2015

4

Design, synthesis and in vitro evaluation against human cancer cells of 5-methyl-5-styryl-2,5-dihydrofuran-2-ones, a new series of goniothalamin analogues

Bruder, Marjorie, Vendramini-Costa, Débora Barbosa, de Carvalho, João Ernesto, Pilli, Ronaldo Aloise

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 939 KB

english, 2013

5

Antiproliferative Effect of Synadenium grantii Hook f. stems (Euphorbiaceae) and a Rare Phorbol Diterpene Ester

Campos, A., Vendramini-Costa, D. B., Longato, G. B., Zermiani, T., Ruiz, A. L. T. G., de Carvalho, J. E., Pandiella, A., Cechinel Filho, V.

Journal:

International Journal of Toxicology

Year:

2016

Language:

english

File:

PDF, 210 KB

english, 2016

6

Uncommon Trimethoxylated Flavonol Obtained from Rubus rosaefolius Leaves and Its Antiproliferative Activity

Petreanu, Marcel, Ferreira, Emili Kamila, Sagaz, Ana Paula M., Vendramini-Costa, Débora B., Ruiz, Ana Lúcia T. G., De Carvalho, João Ernesto, Campos, Adriana, Cechinel Filho, Valdir, Delle Monache, Fr

Journal:

Evidence-based Complementary and Alternative Medicine

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

7

Anticancer and Anti-Inflammatory Activities of a Standardized Dichloromethane Extract from Piper umbellatum L. Leaves

Iwamoto, Leilane Hespporte, Vendramini-Costa, Débora Barbosa, Monteiro, Paula Araújo, Ruiz, Ana Lúcia Tasca Gois, Sousa, Ilza Maria de Oliveira, Foglio, Mary Ann, de Carvalho, João Ernesto, Rodrigues,

Journal:

Evidence-based Complementary and Alternative Medicine

Year:

2015

Language:

english

File:

PDF, 1.41 MB

english, 2015

8

Effect of goniothalamin on the development of Ehrlich solid tumor in mice

Débora Barbosa Vendramini-Costa, Ilton Barros Daltro de Castro, Ana Lúcia Tasca Góis Ruiz, Cilene Marquissolo, Ronaldo Aloise Pilli, João Ernesto de Carvalho

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 366 KB

english, 2010

9

Antiproliferative Activity of Three Methoxylated Flavonoids Isolated from Zeyheria montana Mart. (Bignoniaceae) Leaves

Leonardo Noboru Seito, Ana Lucia Tasca Goiz Ruiz, Debora Vendramini-Costa, Sirlene Valério Tinti, João Ernesto de Carvalho, Jairo Kenupp Bastos, Luiz Claudio Di Stasi

Journal:

Phytotherapy Research

Year:

2011

Language:

english

File:

PDF, 97 KB

english, 2011

10

Synthesis of methoxylated goniothalamin, aza-goniothalamin and γ-pyrones and their in vitro evaluation against human cancer cells

Rosimeire Coura Barcelos, Julio Cezar Pastre, Vanessa Caixeta, Débora Barbosa Vendramini-Costa, João Ernesto de Carvalho, Ronaldo Aloise Pilli

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 531 KB

english, 2012

11

The antinociceptive activity of harmicine on chemical-induced neurogenic and inflammatory pain models in mice

Humberto M. Spindola, Débora B. Vendramini-Costa, Manoel T. Rodrigues Jr., Mary A. Foglio, Ronaldo A. Pilli, João E. Carvalho

Journal:

Pharmacology Biochemistry and Behavior

Year:

2012

Language:

english

File:

PDF, 635 KB

english, 2012

12

Pharmacological characterization ofSolanum cernuumVell.: 31-norcycloartanones with analgesic and anti-inflammatory properties

Lopes, Luciane C., Carvalho, João Ernesto, Kakimore, Marise, Vendramini-Costa, Débora B., Medeiros, Maria A., Spindola, Humberto M., Ávila-Román, Javier, Lourenço, Ana M., Motilva, Virginia

Journal:

Inflammopharmacology

Year:

2014

Language:

english

File:

PDF, 358 KB

english, 2014

13

Oncibauerins A and B, new flavanones from Oncidium baueri (Orchidaceae)

Monteiro, Josiane A., Schuquel, Ivânia T.A., de Almeida, Thiago L., Santin, Silvana M. de O., da Silva, Cleuza C., Chiavelli, Lucas U.R., Ruiz, Ana L.T.G., de Carvalho, João E., Vendramini-Costa, Débo

Journal:

Phytochemistry Letters

Year:

2014

Language:

english

File:

PDF, 627 KB

english, 2014

14

337: STAT3, IL-17 and COX-2 features in the transgenic adenocarcinoma of mouse prostate (TRAMP) model and in the aging mice (FVB) submitted to goniothalamin therapy

Kido, L.A., Montico, F., Vendramini-Costa, D.B., Carvalho, J.E., Pilli, R.A., Cagnon, V.H.A.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 66 KB

english, 2014

15

Design and Synthesis of N-Acylated Aza-Goniothalamin Derivatives and Evaluation of Their in vitro and in vivo Antitumor Activity

Barcelos, Rosimeire Coura, Pastre, Julio Cezar, Vendramini-Costa, Débora Barbosa, Caixeta, Vanessa, Longato, Giovanna Barbarini, Monteiro, Paula Araújo, de Carvalho, João Ernesto, Pilli, Ronaldo Alois

Journal:

Year:

2014

Language:

english

File:

PDF, 1.64 MB

english, 2014

16

Gastroprotective effects of goniothalamin against ethanol and indomethacin-induced gastric lesions in rats: Role of prostaglandins, nitric oxide and sulfhydryl compounds

Vendramini-Costa, Débora Barbosa, Monteiro, Karin Maia, Iwamoto, Leilane Hespporte, Jorge, Michelle Pedroza, Tinti, Sirlene Valério, Pilli, Ronaldo Aloise, de Carvalho, João Ernesto

Journal:

Chemico-Biological Interactions

Year:

2014

Language:

english

File:

PDF, 496 KB

english, 2014

17

Antiproliferative activity of synthetic fatty acid amides from renewable resources

dos Santos, Daiane S., Piovesan, Luciana A., D’Oca, Caroline R. Montes, Hack, Carolina R. Lopes, Treptow, Tamara G.M., Rodrigues, Marieli O., Vendramini-Costa, Débora B., Ruiz, Ana Lucia T.G., de Carv

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 2.02 MB

english, 2015

18

Different cell death responses induced by eupomatenoid-5 in MCF-7 and 786-0 tumor cell lines

Longato, Giovanna Barbarini, Fiorito, Giovanna Francisco, Vendramini-Costa, Débora Barbosa, Sousa, Ilza Maria de Oliveira, Tinti, Sirlene Valério, Ruiz, Ana Lúcia Tasca Gois, Almeida, Sinara Mônica Vi

Journal:

Toxicology in Vitro

Year:

2015

Language:

english

File:

PDF, 1.09 MB

english, 2015

19

Anti-inflammatory and antinociceptive effects of racemic goniothalamin, a styryl lactone

Vendramini-Costa, Débora Barbosa, Spindola, Humberto Moreira, de Mello, Glaucia Coelho, Antunes, Edson, Pilli, Ronaldo Aloise, de Carvalho, João Ernesto

Journal:

Year:

2015

Language:

english

File:

PDF, 791 KB

english, 2015

20

Antiproliferative effect of extracts and pyranonaphthoquinones obtained from Cipura paludosa bulbs

Campos, Adriana, Barbosa Vendramini-Costa, Débora, Francisco Fiorito, Giovanna, Lúcia Tasca Gois Ruiz, Ana, Ernesto de Carvalho, João, Maria Rodrigues de Souza, Greice, Delle-Monache, Franco, Cechinel

Journal:

Pharmaceutical Biology

Year:

2015

Language:

english

File:

PDF, 807 KB

english, 2015

21

In vitro antiproliferative activity of uncommon xanthones from branches of Garcinia achachairu

Mariano, Luisa Nathália Bolda, Vendramini-Costa, Débora Barbosa, Ruiz, Ana Lúcia Tasca Gois, de Carvalho, João Ernesto, Corrêa, Rogério, Cechinel Filho, Valdir, Delle Monache, Franco, Niero, Rivaldo

Journal:

Pharmaceutical Biology

Year:

2015

Language:

english

File:

PDF, 977 KB

english, 2015

22

Goniothalamin prevents the development of chemically induced and spontaneous colitis in rodents and induces apoptosis in the HT-29 human colon tumor cell line

Vendramini-Costa, Débora Barbosa, Alcaide, Antonio, Pelizzaro-Rocha, Karin Juliane, Talero, Elena, Ávila-Román, Javier, Garcia-Mauriño, Sofia, Pilli, Ronaldo Aloise, de Carvalho, João Ernesto, Motilva

Journal:

Toxicology and Applied Pharmacology

Year:

2016

Language:

english

File:

PDF, 757 KB

english, 2016

23

Expression patterns of sirtuin 1-AMPK-autophagy pathway in chronic colitis and inflammation-associated colon neoplasia in IL-10-deficient mice

Talero, Elena, Alcaide, Antonio, Ávila-Román, Javier, García-Mauriño, Sofía, Vendramini-Costa, Débora, Motilva, Virginia

Journal:

International Immunopharmacology

Year:

2016

Language:

english

File:

PDF, 2.05 MB

english, 2016

24

(−)-Tarchonanthuslactone: Design of New Analogues, Evaluation of their Antiproliferative Activity on Cancer Cell Lines, and Preliminary Mechanistic Studies

Toneto Novaes, Luiz Fernando, Martins Avila, Carolina, Pelizzaro-Rocha, Karin Juliane, Vendramini-Costa, Débora Barbosa, Pereira Dias, Marina, Barbosa Trivella, Daniela Barreto, Ernesto de Carvalho, J

Journal:

Year:

2015

Language:

english

File:

PDF, 1.09 MB

english, 2015

25

Diastereoselective Synthesis of Biologically Active Cyclopenta[b]indoles

Santos, Marilia Simão, Fernandes, Daniara Cristina, Rodrigues, Manoel T., Regiani, Thais, Andricopulo, Adriano Defini, Ruiz, Ana Lucia Tasca Gois, Vendramini-Costa, Débora Barbosa, Carvalho, João Erne

Journal:

Journal of Organic Chemistry

Year:

2016

Language:

english

File:

PDF, 980 KB

english, 2016

26

Anti-inflammatory natural product goniothalamin reduces colitis-associated and sporadic colorectal tumorigenesis.

Barbosa Vendramini-Costa, Débora, Francescone, Ralph, Posocco, David, Hou, Vivianty, Dmitrieva, Oxana, Hensley, Harvey, de Carvalho, João Ernesto, Pilli, Ronaldo Aloise, Grivennikov, Sergei

Journal:

Year:

2016

Language:

english

File:

PDF, 11.28 MB

english, 2016

27

Goniothalamin and Celecoxib Effects During Aging: Targeting Pro-Inflammatory Mediators in Chemoprevention of Prostatic Disorders

Kido, Larissa Akemi, Montico, Fabio, Vendramini-Costa, Débora Barbosa, Pilli, Ronaldo Aloise, Cagnon, Valeria Helena Alves

Journal:

Year:

2017

Language:

english

File:

PDF, 5.19 MB

english, 2017

28

Characterization of phenolic compounds in chia ( Salvia hispanica L.) seeds, fiber flour and oil

Oliveira-Alves, Sheila Cristina, Vendramini-Costa, Débora Barbosa, Betim Cazarin, Cinthia Baú, Maróstica Júnior, Mário Roberto, Borges Ferreira, João Pedro, Silva, Andreia Bento, Prado, Marcelo Alexan

Journal:

Year:

2017

Language:

english

File:

PDF, 521 KB

english, 2017

29

Thiosemicarbazones and 4-thiazolidinones indole-based derivatives: Synthesis, evaluation of antiproliferative activity, cell death mechanisms and topoisomerase inhibition assay

de Oliveira, Jamerson Ferreira, Lima, Talitha Santos, Vendramini-Costa, Débora Barbosa, de Lacerda Pedrosa, Sybelle Christianne Batista, Lafayette, Elizabeth Almeida, da Silva, Rosali Maria Ferreira,

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 730 KB

english, 2017

30

Chemical composition and antiproliferative activity of Croton campestris A.St.-Hil. essential oil

Araújo Monteiro, Paula, Maccari Zelioli, Ícaro Augusto, de Oliveira Sousa, Ilza Maria, Ruiz, Ana Lúcia Tasca Gois, Vendramini-Costa, Débora Barbosa, Foglio, Mary Ann, Carvalho, João Ernesto de

Journal:

Natural Product Research

Year:

2017

Language:

english

File:

PDF, 729 KB

english, 2017

31

ChemInform Abstract: Diastereoselective Synthesis of Biologically Active Cyclopenta[b]indoles.

Santos, Marilia S., Fernandes, Daniara C., Rodrigues, Manoel T., Regiani, Thais, Andricopulo, Adriano D., Ruiz, Ana Lucia T. G., Vendramini-Costa, Debora B., de Carvalho, Joao E., Eberlin, Marcos N.,

Journal:

Year:

2016

File:

PDF, 33 KB

2016

32

Steroidal hormone and morphological responses in the prostate anterior lobe in different cancer grades after Celecoxib and Goniothalamin treatments in TRAMP mice

Silva, Rafael Sauce, Kido, Larissa Akemi, Montico, Fabio, Vendramini-Costa, Débora Barbosa, Pilli, Ronaldo Aloise, Cagnon, Valeria Helena Alves

Journal:

Cell Biology International

Year:

2018

Language:

english

File:

PDF, 2.39 MB

english, 2018

33

Netrin G1 promotes pancreatic tumorigenesis through cancer associated fibroblast driven nutritional support and immunosuppression

Francescone, Ralph, Barbosa Vendramini-Costa, DÃ©bora, Franco-Barraza, Janusz, Wagner, Jessica, Muir, Alexander, Lau, Allison N, Gabitova, Linara, Pazina, Tatiana, Gupta, Sapna, Luong, Tiffany, Rollin

Journal:

Cancer Discovery

Year:

2020

File:

PDF, 5.22 MB

2020

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